The STAT3 gene homepage

General information
Gene symbol STAT3
Gene name signal transducer and activator of transcription 3 (acute-phase response factor)
Chromosome 17
Chromosomal band q21
Imprinted Unknown
Genomic reference NG_007370.1
Transcript reference NM_003150.3, NM_139276.2, NM_213662.1, XM_005257613.1, XM_005257614.1, XM_005257615.1, XM_005257616.1, XM_005257617.1, XM_005257618.1, XM_005257619.1, XM_005257620.1
Associated with diseases ADMIO, Hyperimmunoglobulin E syndrome
Citation reference(s) -
Curators (1) Johan T. den Dunnen
Total number of public variants reported 97
Unique public DNA variants reported 13
Individuals with public variants 34
Hidden variants 71
Date created October 30, 2013
Date last updated September 28, 2016
Version STAT3:160928

Graphical displays and utilities
Graphs Graphs displaying summary information of all variants in the database »
UCSC Genome Browser Show variants in the UCSC Genome Browser (full view, compact view)
Ensembl Genome Browser Show variants in the Ensembl Genome Browser (full view, compact view)
NCBI Sequence Viewer Show distribution histogram of variants in the NCBI Sequence Viewer

Links to other resources
External URL List of LSDBs for this gene
The reference LOVD for this gene, if available
HGNC HGNC:11364
Entrez Gene 6774
PubMed articles STAT3
OMIM - Gene 102582
OMIM - Diseases ADMIO (autoimmune disease, multisystem, infantile-onset (ADMIO))
Hyperimmunoglobulin E syndrome
HGMD STAT3
GeneCards STAT3
GeneTests STAT3


Active transcripts


ID     

Chr     

Name     

NCBI ID     

NCBI Protein ID     

DescendingVariants     
00007642 17 transcript variant 2 NM_003150.3 NP_003141.2 97
00007643 17 transcript variant 1 NM_139276.2 NP_644805.1 97
00019883 17 Manually created transcript. NM_213662.1 - 97
00038494 17 transcript variant X2 XM_005257614.1 XP_005257671.1 -
00038495 17 transcript variant X4 XM_005257616.1 XP_005257673.1 -
00038496 17 transcript variant X5 XM_005257617.1 XP_005257674.1 -
00038497 17 transcript variant X8 XM_005257620.1 XP_005257677.1 -
00038498 17 transcript variant X6 XM_005257618.1 XP_005257675.1 -
00038499 17 transcript variant X7 XM_005257619.1 XP_005257676.1 -
00038500 17 transcript variant X1 XM_005257613.1 XP_005257670.1 -
00038501 17 transcript variant X3 XM_005257615.1 XP_005257672.1 -


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