CYP2A6 gene homepage

General information
Gene symbol CYP2A6
Gene name cytochrome P450, family 2, subfamily A, polypeptide 6
Chromosome 19
Chromosomal band q13.2
Imprinted Not imprinted
Genomic reference NG_008377.1
Transcript reference NM_000762.5
Exon/intron information NM_000762.5 exon/intron table
Associated with diseases ACLC, DMB-CYP2A6, addiction, tobacco, susceptibility to
Citation reference(s) -
Refseq URL Genomic reference sequence
Curators (1) LOVD-team, but with Curator vacancy
Total number of public variants reported 811
Unique public DNA variants reported 179
Individuals with public variants 135
Hidden variants 0
Download all this gene's data Download all data
Notes Establishment of this gene variant database (LSDB) was supported by the Leiden University Medical Center (LUMC), Leiden, Nederland.
Date created May 03, 2013
Date last updated October 27, 2018
Version CYP2A6:181027

Graphical displays and utilities
Graphs Graphs displaying summary information of all variants in the database »
Reading frame checker The Reading-frame checker generates a prediction of the effect of whole-exon changes. Active for: NM_000762.5.
UCSC Genome Browser Show variants in the UCSC Genome Browser (full view, compact view)
Ensembl Genome Browser Show variants in the Ensembl Genome Browser (full view, compact view)
NCBI Sequence Viewer Show distribution histogram of variants in the NCBI Sequence Viewer

Links to other resources
Homepage URL https://www.LOVD.nl/CYP2A6
HGNC 2610
Entrez Gene 1548
PubMed articles CYP2A6
OMIM - Gene 122720
OMIM - Diseases ACLC (cancer, lung (adenocarcinoma))
DMB-CYP2A6 (metabolism, drug, resistance, coumarin)
addiction, tobacco, susceptibility to
HGMD CYP2A6
GeneCards CYP2A6
GeneTests CYP2A6


Active transcripts


ID     

Chr     

Name     

NCBI ID     

NCBI Protein ID     

DescendingVariants     
00005994 19 cytochrome P450, family 2, subfamily A, polypeptide 6 NM_000762.5 NP_000753.3 811


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