Disease #00639 (cancer, lung (cancer, lung (adenocarcinoma)), OMIM:211980)

Official abbreviation	cancer, lung
Name	cancer, lung (adenocarcinoma)
OMIM ID	211980
Human Phenotype Ontology Project (HPO)	HPO
Inheritance	-
Individuals reported having this disease	53
Phenotype entries for this disease	41
Associated with 17 genes	BRAF, CASP8, CYP2A6, DLEC1, EGFR, ERBB2, ERCC6, FASLG, IRF1, KRAS, MAP3K8, PARK2, PIK3CA, PPP2R1B, RASSF1, SFTPA2, SLC22A18
Associated tissues	-
Disease features	-
Remarks	-
Date created	2014-09-25 23:29:40 +02:00 (CEST)
Date last edited	2021-12-10 21:51:32 +01:00 (CET)

Individuals

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Please note that a short description of a certain column can be displayed when you move your mouse cursor over the column's header and hold it still. Below, a more detailed description is shown per column.

ID_report: ID of the individual that can be publically shared, e.g. as listed in a publication

Reference: reference to publication describing the individual/family, possibly giving more phenotypic details than listed in this database entry, incl. link to PubMed or other source, e.g. "den Dunnen ASHG2003 P2346"

Remarks: remarks about the individual

Gender: gender individual
All options:

? = unknown
- = not applicable
F = female
M = male
rF = raised as female
rM = raised as male

Consanguinity: indicates whether the parents are related (consanguineous), not related (non-consanguineous) or whether consanguinity is not known (unknown)
All options:

no = non-consanguineous parents
yes = consanguineous parents
likely = consanguinity likely
? = unknown
- = not applicable

Country: where (country) does the individual live/recently came from. Give additional details (population, specific sub-group) and when parents come from different countries in "Population". Belgium = individual lives in/recently came from Belgium, (France) = reported by laboratory in France, individual's country of origin not sure
All options:

? (unknown)
- (not applicable)
Afghanistan
(Afghanistan)
Albania
(Albania)
Algeria
(Algeria)
American Samoa
(American Samoa)
Andorra
(Andorra)
Angola
(Angola)
Anguilla
(Anguilla)
Antarctica
(Antarctica)
Antigua and Barbuda
(Antigua and Barbuda)
Argentina
(Argentina)
Armenia
(Armenia)
Aruba
(Aruba)
Australia
(Australia)
Austria
(Austria)
Azerbaijan
(Azerbaijan)
Bahamas
(Bahamas)
Bahrain
(Bahrain)
Bangladesh
(Bangladesh)
Barbados
(Barbados)
Belarus
(Belarus)
Belgium
(Belgium)
Belize
(Belize)
Benin
(Benin)
Bermuda
(Bermuda)
Bhutan
(Bhutan)
Bolivia
(Bolivia)
Bosnia and Herzegovina
(Bosnia and Herzegovina)
Botswana
(Botswana)
Bouvet Island
(Bouvet Island)
Brazil
(Brazil)
British Indian Ocean Territory
(British Indian Ocean Territory)
Brunei Darussalam
(Brunei Darussalam)
Bulgaria
(Bulgaria)
Burkina Faso
(Burkina Faso)
Burundi
(Burundi)
Cambodia
(Cambodia)
Cameroon
(Cameroon)
Canada
(Canada)
Cape Verde
(Cape Verde)
Cayman Islands
(Cayman Islands)
Central African Republic
(Central African Republic)
Central Europe
Chad
(Chad)
Chile
(Chile)
China
(China)
Christmas Island
(Christmas Island)
Cocos (Keeling Islands)
(Cocos (Keeling Islands))
Colombia
(Colombia)
Comoros
(Comoros)
Congo
(Congo)
Cook Islands
(Cook Islands)
Costa Rica
(Costa Rica)
Cote D'Ivoire (Ivory Coast)
(Cote D'Ivoire (Ivory Coast))
Croatia (Hrvatska)
(Croatia (Hrvatska))
Cuba
(Cuba)
Cyprus
(Cyprus)
Czech Republic
(Czech Republic)
Denmark
(Denmark)
Djibouti
(Djibouti)
Dominica
(Dominica)
Dominican Republic
(Dominican Republic)
East Timor
(East Timor)
Ecuador
(Ecuador)
Egypt
(Egypt)
El Salvador
(El Salvador)
England
(England)
Equatorial Guinea
(Equatorial Guinea)
Eritrea
(Eritrea)
Estonia
(Estonia)
Ethiopia
(Ethiopia)
Falkland Islands (Malvinas)
(Falkland Islands (Malvinas))
Faroe Islands
(Faroe Islands)
Fiji
(Fiji)
Finland
(Finland)
France
(France)
Gabon
(Gabon)
Gambia
(Gambia)
Georgia
(Georgia)
Germany
(Germany)
Ghana
(Ghana)
Gibraltar
(Gibraltar)
Greece
(Greece)
Greenland
(Greenland)
Grenada
(Grenada)
Guadeloupe
(Guadeloupe)
Guam
(Guam)
Guatemala
(Guatemala)
Guiana, French
(Guiana, French)
Guinea
(Guinea)
Guinea-Bissau
(Guinea-Bissau)
Guyana
(Guyana)
Haiti
(Haiti)
Heard and McDonald Islands
(Heard and McDonald Islands)
Honduras
(Honduras)
Hong Kong
(Hong Kong)
Hungary
(Hungary)
Iceland
(Iceland)
India
(India)
Indonesia
(Indonesia)
Iran
(Iran)
Iraq
(Iraq)
Ireland
(Ireland)
Israel
(Israel)
Italy
(Italy)
Jamaica
(Jamaica)
Japan
(Japan)
Jordan
(Jordan)
Kazakhstan
(Kazakhstan)
Kenya
(Kenya)
Kiribati
(Kiribati)
Korea
(Korea)
Korea, North (People's Republic)
(Korea, North (People's Republic))
Korea, South (Republic)
(Korea, South (Republic))
Kosovo
(Kosovo)
Kuwait
(Kuwait)
Kyrgyzstan (Kyrgyz Republic)
(Kyrgyzstan (Kyrgyz Republic))
Laos
(Laos)
Latvia
(Latvia)
Lebanon
(Lebanon)
Lesotho
(Lesotho)
Liberia
(Liberia)
Libya
(Libya)
Liechtenstein
(Liechtenstein)
Lithuania
(Lithuania)
Luxembourg
(Luxembourg)
Macau
(Macau)
Macedonia
(Macedonia)
Madagascar
(Madagascar)
Malawi
(Malawi)
Malaysia
(Malaysia)
Maldives
(Maldives)
Mali
(Mali)
Mallorca
(Mallorca)
Malta
(Malta)
Marshall Islands
(Marshall Islands)
Martinique
(Martinique)
Mauritania
(Mauritania)
Mauritius
(Mauritius)
Mayotte
(Mayotte)
Mexico
(Mexico)
Micronesia
(Micronesia)
Moldova
(Moldova)
Monaco
(Monaco)
Mongolia
(Mongolia)
Montserrat
(Montserrat)
Morocco
(Morocco)
Mozambique
(Mozambique)
Myanmar
(Myanmar)
Namibia
(Namibia)
Nauru
(Nauru)
Nepal
(Nepal)
Netherlands
(Netherlands)
Netherlands Antilles
(Netherlands Antilles)
Neutral Zone (Saudia Arabia/Iraq)
(Neutral Zone (Saudia Arabia/Iraq))
New Caledonia
(New Caledonia)
New Zealand
(New Zealand)
Nicaragua
(Nicaragua)
Niger
(Niger)
Nigeria
(Nigeria)
Niue
(Niue)
Norfolk Island
(Norfolk Island)
Northern Ireland
(Northern Ireland)
Northern Mariana Islands
(Northern Mariana Islands)
Norway
(Norway)
Oman
(Oman)
Pakistan
(Pakistan)
Palau
(Palau)
Palestine
(Palestine)
Panama
(Panama)
Papua New Guinea
(Papua New Guinea)
Paraguay
(Paraguay)
Peru
(Peru)
Philippines
(Philippines)
Pitcairn
(Pitcairn)
Poland
(Poland)
Polynesia, French
(Polynesia, French)
Portugal
(Portugal)
Puerto Rico
(Puerto Rico)
Qatar
(Qatar)
Reunion
(Reunion)
Romania
(Romania)
Russia
(Russia)
Russian Federation
(Russian Federation)
Rwanda
(Rwanda)
S. Georgia and S. Sandwich Isls.
(S. Georgia and S. Sandwich Isls.)
Saint Kitts and Nevis
(Saint Kitts and Nevis)
Saint Lucia
(Saint Lucia)
Saint Vincent and The Grenadines
(Saint Vincent and The Grenadines)
Samoa
(Samoa)
San Marino
(San Marino)
Sao Tome and Principe
(Sao Tome and Principe)
Saudi Arabia
(Saudi Arabia)
Scotland
(Scotland)
Senegal
(Senegal)
Serbia
(Serbia)
Seychelles
(Seychelles)
Sierra Leone
(Sierra Leone)
Singapore
(Singapore)
Slovakia (Slovak Republic)
(Slovakia (Slovak Republic))
Slovenia
(Slovenia)
Solomon Islands
(Solomon Islands)
Somalia
(Somalia)
South Africa
(South Africa)
Southern Territories, French
(Southern Territories, French)
Soviet Union (former)
(Soviet Union (former))
Spain
(Spain)
Sri Lanka
(Sri Lanka)
St. Helena, Ascension and Tristan da
Cunha
(St. Helena, Ascension and Tristan da
Cunha)
St. Pierre and Miquelon
(St. Pierre and Miquelon)
Sudan
(Sudan)
Sudan, South
(Sudan, South)
Suriname
(Suriname)
Svalbard and Jan Mayen Islands
(Svalbard and Jan Mayen Islands)
Swaziland
(Swaziland)
Sweden
(Sweden)
Switzerland
(Switzerland)
Syria
(Syria)
Taiwan
(Taiwan)
Tajikistan
(Tajikistan)
Tanzania
(Tanzania)
Thailand
(Thailand)
Togo
(Togo)
Tokelau
(Tokelau)
Tonga
(Tonga)
Trinidad and Tobago
(Trinidad and Tobago)
Tunisia
(Tunisia)
Turkey
(Turkey)
Turkmenistan
(Turkmenistan)
Turks and Caicos Islands
(Turks and Caicos Islands)
Tuvalu
(Tuvalu)
Uganda
(Uganda)
Ukraine
(Ukraine)
United Arab Emirates
(United Arab Emirates)
United Kingdom (Great Britain)
(United Kingdom (Great Britain))
United States
(United States)
Uruguay
(Uruguay)
US Minor Outlying Islands
(US Minor Outlying Islands)
Uzbekistan
(Uzbekistan)
Vanuatu
(Vanuatu)
Vatican City State (Holy See)
(Vatican City State (Holy See))
Venezuela
(Venezuela)
Viet Nam
(Viet Nam)
Virgin Islands (British)
(Virgin Islands (British))
Virgin Islands (US)
(Virgin Islands (US))
Wales
(Wales)
Wallis and Futuna Islands
(Wallis and Futuna Islands)
Western Sahara
(Western Sahara)
Yemen
(Yemen)
Yugoslavia
(Yugoslavia)
Zaire
(Zaire)
Zambia
(Zambia)
Zimbabwe
(Zimbabwe)

Population: population the individual (or ancestors) belongs to; e.g. white, gypsy, Jewish-Ashkenazi, Africa-N, Sardinia, etc.

Age at death: age at which the individual deceased (when applicable):

35y = 35 years
>43y = still alive at 43y
04y08m = 4 years and 8 months
00y00m01d12h = 1 day and 12 hours
18y? = around 18 years
30y-40y = between 30 and 40 years
>54y = older than 54
? = unknown

VIP: individual/phenotype VIP-status was requested for matchmaking - need collaboration(s) to crack the case - please contact the submitter/curator. NOTE: to get VIP status ask the curator.

Data_av: are additional data available upon request: e.g. pedigree (yes/no/?)

Treatment: treatment of patient

Variants in genes: The individual has variants for this gene.

Panel size: Number of individuals this entry represents; e.g. 1 for an individual, 5 for a family with 5 affected members.

How to query this table

All list views have search fields which can be used to search data. You can search for a complete word or you can search for a part of a search term. If you enclose two or more words in double quotes, LOVD will search for the combination of those words only exactly in the order you specify. Note that search terms are case-insensitive and that wildcards such as * are treated as normal text! For all options, like "and", "or", and "not" searches, or searching for prefixes or suffixes, see the table below.

Operator	Column type	Example	Matches
	Text	Arg	all entries containing 'Arg'
space	Text	Arg Ser	all entries containing 'Arg' and 'Ser'
\|	Text	Arg\|Ser	all entries containing 'Arg' or 'Ser'
!	Text	!fs	all entries not containing 'fs'
^	Text	^p.(Arg	all entries beginning with 'p.(Arg'
$	Text	Ser)$	all entries ending with 'Ser)'
=""	Text	=""	all entries with this field empty
=""	Text	="p.0"	all entries exactly matching 'p.0'
!=""	Text	!=""	all entries with this field not empty
!=""	Text	!="p.0"	all entries not exactly matching 'p.0?'
combination	Text	*\|Ter !fs	all entries containing '*' or 'Ter' but not containing 'fs'
	Date	2020	all entries matching the year 2020
\|	Date	2020-03\|2020-04	all entries matching March or April, 2020
!	Date	!2020-03	all entries not matching March, 2020
<	Date	<2020	all entries before the year 2020
<=	Date	<=2020-06	all entries in or before June, 2020
>	Date	>2020-06	all entries after June, 2020
>=	Date	>=2020-06-15	all entries on or after June 15th, 2020
combination	Date	2019\|2020 <2020-03	all entries in 2019 or 2020, and before March, 2020
	Numeric	23	all entries exactly matching 23
\|	Numeric	23\|24	all entries exactly matching 23 or 24
!	Numeric	!23	all entries not exactly matching 23
<	Numeric	<23	all entries lower than 23
<=	Numeric	<=23	all entries lower than, or equal to, 23
>	Numeric	>23	all entries higher than 23
>=	Numeric	>=23	all entries higher than, or equal to, 23
combination	Numeric	>=20 <30 !23	all entries with values from 20 to 29, but not equal to 23

Some more advanced examples:

Example	Matches
Asian	all entries containing 'Asian', 'asian', including 'Caucasian', 'caucasian', etc.
Asian !Caucasian	all entries containing 'Asian' but not containing 'Caucasian'
Asian\|African !Caucasian	all entries containing 'Asian' or 'African', but not containing 'Caucasian'
"South Asian"	all entries containing 'South Asian', but not containing 'South East Asian'

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53 entries on 1 page. Showing entries 1 - 53.

Legend

How to query

Individual ID	ID_report	Reference	Remarks	Gender	Consanguinity	Country	Population	Age at death	VIP	Data_av	Treatment	Disease	Phenotype details	Genes screened	Variants in genes	Variants	Panel size	Owner
00034549	-	-	-	-	-	France	-	-	-	-	-	cancer, lung	lung cancer	KRAS	KRAS	1	1	Johan den Dunnen
00034551	-	-	-	-	-	France	-	-	-	-	-	cancer, lung	lung cancer	KRAS	KRAS	1	1	Johan den Dunnen
00047907	-	-	-	-	-	-	-	-	-	-	-	cancer, lung	-	ARID1A	ARID1A	1	1	Sian Jones
00047908	-	-	-	-	-	-	-	-	-	-	-	cancer, lung	-	ARID1A	ARID1A	1	1	Sian Jones
00048008	-	-	-	-	-	-	-	-	-	-	-	cancer, lung	-	SMARCA4	SMARCA4	1	1	Global Variome, with Curator vacancy
00058107	-	-	-	-	-	-	-	-	-	-	-	cancer, lung	lung, adenocarcinoma	TTN	TTN	2	1	Johan den Dunnen
00105378	?	PubMed: Ulybina 2009	-	-	-	-	-	-	-	-	-	cancer, lung	Lung cancer	TNFRSF10A	TNFRSF10A	1	1	Zoe Baily
00105381	?	PubMed: Ulybina 2009	-	-	-	-	-	-	-	-	-	cancer, lung	Lung cancer	TNFRSF10A	TNFRSF10A	1	1	Zoe Baily
00105388	?	PubMed: Ulybina 2009	-	-	-	-	-	-	-	-	-	cancer, lung	Lung cancer	TNFRSF10A	TNFRSF10A	1	1	Zoe Baily
00105401	?	PubMed: Ulybina 2009	-	-	-	-	-	-	-	-	-	cancer, lung	Lung cancer	TNFRSF10A	TNFRSF10A	1	1	Zoe Baily
00124380	19937601.p	PubMed: Flanigan 2009	-	-	-	United States	-	-	-	-	-	cancer, lung, DMD	-	DMD	DMD	1	106	Kevin Flanigan
00124381	19937601.p	PubMed: Flanigan 2009	-	-	-	United States	-	-	-	-	-	cancer, lung, DMD	-	DMD	DMD	1	11	Kevin Flanigan
00124382	19937601.p	PubMed: Flanigan 2009	-	-	-	United States	-	-	-	-	-	cancer, lung, DMD	-	DMD	DMD	1	11	Kevin Flanigan
00124383	19937601.p	PubMed: Flanigan 2009	-	M	-	United States	-	-	-	-	-	cancer, lung, DMD	-	DMD	DMD	1	11	Kevin Flanigan
00124384	19937601.p	PubMed: Flanigan 2009	-	-	-	United States	-	-	-	-	-	cancer, lung, DMD	-	DMD	DMD	1	12	Kevin Flanigan
00124385	19937601.p	PubMed: Flanigan 2009	-	-	-	United States	-	-	-	-	-	cancer, lung, DMD	-	DMD	DMD	1	121	Kevin Flanigan
00124386	19937601.p	PubMed: Flanigan 2009	-	M	-	United States	-	-	-	-	-	cancer, lung, DMD	-	DMD	DMD	1	126	Kevin Flanigan
00124387	19937601.p	PubMed: Flanigan 2009	-	-	-	United States	-	-	-	-	-	cancer, lung, DMD	-	DMD	DMD	1	13	Kevin Flanigan
00124389	19937601.p	PubMed: Flanigan 2009	-	-	-	United States	-	-	-	-	-	cancer, lung, DMD	-	DMD	DMD	1	16	Kevin Flanigan
00141882	-	PubMed: Flanigan 2009	-	M	-	United States	-	-	-	-	-	cancer, lung, DMD	-	DMD	DMD	1	1	Kevin Flanigan
00149417	-	-	-	-	-	-	-	-	-	-	-	cancer, lung, FTD	-	GRN	GRN	1	1	Marc Cruts
00149696	-	-	-	-	-	Italy	white	-	-	-	-	ALS10, cancer, lung	-	TARDBP	TARDBP	1	1	Marc Cruts
00149698	-	-	-	-	-	Italy	white	-	-	-	-	ALS10, cancer, lung	-	TARDBP	TARDBP	1	1	Marc Cruts
00149699	-	-	-	-	-	Italy	white	-	-	-	-	ALS10, cancer, lung	-	TARDBP	TARDBP	1	1	Marc Cruts
00149701	-	-	-	-	-	Italy	white	-	-	-	-	ALS10, cancer, lung	-	TARDBP	TARDBP	1	1	Marc Cruts
00149702	-	-	-	-	-	Italy	white	-	-	-	-	ALS10, cancer, lung	-	TARDBP	TARDBP	1	1	Marc Cruts
00149703	-	-	-	-	-	Italy	white	-	-	-	-	ALS10, cancer, lung	-	TARDBP	TARDBP	1	1	Marc Cruts
00149893	-	-	-	-	-	Finland	white	-	-	-	-	cancer, lung, FTDALS	-	C9orf72	-	-	1	Marc Cruts
00149894	-	-	-	-	-	Finland	white	-	-	-	-	cancer, lung, FTDALS	-	C9orf72	-	-	1	Marc Cruts
00149895	-	-	-	-	-	Finland	white	-	-	-	-	cancer, lung, FTDALS	-	C9orf72	-	-	1	Marc Cruts
00149907	-	-	-	-	-	Finland	white	-	-	-	-	cancer, lung, FTDALS	-	C9orf72	-	-	1	Marc Cruts
00149911	-	-	-	-	-	Finland	white	-	-	-	-	cancer, lung, FTDALS	-	C9orf72	-	-	1	Marc Cruts
00149912	-	-	-	-	-	Finland	white	-	-	-	-	cancer, lung, FTDALS	-	C9orf72	-	-	1	Marc Cruts
00150738	28610567-Pat182	PubMed: Deepha 2017	-	M	-	India	-	-	-	-	-	cancer, lung, DMD	-	DMD	DMD	1	1	Johan den Dunnen
00150740	28610567-Pat184	PubMed: Deepha 2017	-	M	-	India	-	-	-	-	-	cancer, lung, DMD	-	DMD	DMD	1	1	Johan den Dunnen
00150742	28610567-Pat186	PubMed: Deepha 2017	-	M	-	India	-	-	-	-	-	cancer, lung, DMD	-	DMD	DMD	1	1	Johan den Dunnen
00150744	28610567-Pat188	PubMed: Deepha 2017	-	M	-	India	-	-	-	-	-	cancer, lung, DMD	-	DMD	DMD	1	1	Johan den Dunnen
00150746	28610567-Pat190	PubMed: Deepha 2017	-	M	-	India	-	-	-	-	-	cancer, lung, DMD	-	DMD	DMD	1	1	Johan den Dunnen
00150748	28610567-Pat192	PubMed: Deepha 2017	-	M	-	India	-	-	-	-	-	cancer, lung, DMD	-	DMD	DMD	1	1	Johan den Dunnen
00150750	28610567-Pat194	PubMed: Deepha 2017	-	M	-	India	-	-	-	-	-	cancer, lung, DMD	-	DMD	DMD	1	1	Johan den Dunnen
00150752	28610567-Pat196	PubMed: Deepha 2017	-	M	-	India	-	-	-	-	-	cancer, lung, DMD	-	DMD	DMD	1	1	Johan den Dunnen
00150754	28610567-Pat198	PubMed: Deepha 2017	-	M	-	India	-	-	-	-	-	cancer, lung, DMD	-	DMD	DMD	1	1	Johan den Dunnen
00150756	28610567-Pat301	PubMed: Deepha 2017	-	M	-	India	-	-	-	-	-	cancer, lung, DMD	-	DMD	DMD	1	1	Johan den Dunnen
00150758	28610567-Pat303	PubMed: Deepha 2017	-	M	-	India	-	-	-	-	-	cancer, lung, DMD	-	DMD	DMD	1	1	Johan den Dunnen
00150759	28610567-Pat304	PubMed: Deepha 2017	-	M	-	India	-	-	-	-	-	cancer, lung, DMD	-	DMD	DMD	1	1	Johan den Dunnen
00150763	28610567-Pat308	PubMed: Deepha 2017	-	M	-	India	-	-	-	-	-	cancer, lung, DMD	-	DMD	DMD	1	1	Johan den Dunnen
00159062	CIMBA-Fam?	PubMed: Rebbeck 2018, Journal: Rebbeck 2018	1 family	F	-	Italy	white	-	-	-	-	cancer, breast, cancer, lung	-	BRCA2	BRCA2	1	1	Johan den Dunnen
00168061	-	-	-	F	no	Greece	white	00y13m	-	-	-	cancer, lung, SMA1	-	SMN1	SMN1	1	1	Kyriaki Kekou
00183616	-	18282	4 generation FH of CRC, father had CRC at 65y andcarries variant	M	-	United Kingdom (Great Britain)	white	-	-	pedigree	-	cancer, lung	-	-	APC	1	1	Ruth Armstrong
00223174	-	PubMed: Young, 1998	small family	?	-	-	-	-	-	-	-	cancer, lung, TSC	-	TSC1	TSC1	1	2	Rosemary Ekong
00223181	-	PubMed: Young, 1998; PubMed: Jeganathan, 2002	Listed as a problem linked family	?	-	-	-	-	-	-	-	cancer, lung, TSC	-	TSC1	TSC1	1	1	Rosemary Ekong
00265438	-	PubMed: Fu 2018	patient included among primary lung adenocarcinomas cases; asymptomatic; history of smoking; no co-existing disease; physical examination, respiratory function and blood examinations all normal	M	?	China	-	-	-	-	-	cancer, lung	fetal adenocarcinoma of the lung	BRCA1, BRCA2, CTNNB1, TSC1, TSC2	BRCA2, CTNNB1, TSC2	3	1	Rosemary Ekong
00412506	TCGA-78-7148-01	-	-	M	-	-	-	-	-	-	-	cancer, lung	-	-	SMAD9	1	1	Litika Vermani

Legend

How to query

Global Variome shared LOVD