The KRAS gene homepage

General information
Gene symbol KRAS
Gene name v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
Chromosome 12
Chromosomal band p12.1
Imprinted Not imprinted
Genomic reference NG_007524.1
Transcript reference NM_004985.3
Exon/intron information NM_004985.3 exon/intron table
Associated with diseases AML, BAVM, cancer, bladder, cancer, breast, cancer, lung, cancer, pancreatic, CFC1, CFC2, HDGC, ID, NS, NS3, OES, RALD, SFM, Leukemia, acute myelogenous
Citation reference(s) -
Refseq URL Genomic reference sequence
Curators (1) Etienne Rouleau
Total number of public variants reported 97
Unique public DNA variants reported 65
Individuals with public variants 276
Hidden variants 7
Download all this gene's data Download all data
Notes Establishment of this gene variant database (LSDB) was supported by the European Community's Seventh Framework Programme (FP7/2007-2013) under grant agreement No 200754 - the GEN2PHEN project.
Date created April 29, 2010
Date last updated November 01, 2022
Version KRAS:221101

Graphical displays and utilities
Graphs Graphs displaying summary information of all variants in the database »
Reading frame checker The Reading-frame checker generates a prediction of the effect of whole-exon changes. Active for: NM_004985.3.
UCSC Genome Browser Show variants in the UCSC Genome Browser (full view, compact view)
Ensembl Genome Browser Show variants in the Ensembl Genome Browser (full view, compact view)
NCBI Sequence Viewer Show distribution histogram of variants in the NCBI Sequence Viewer

Links to other resources
Homepage URL
HGNC 6407
Entrez Gene 3845
PubMed articles KRAS
OMIM - Gene 190070
OMIM - Diseases AML (leukemia, myeloid, acute (AML))
BAVM (arteriovenous malformation, cerebral, brain (BAVM)
cancer, bladder
cancer, breast (cancer, breast, susceptibility)
cancer, lung (cancer, lung (adenocarcinoma))
cancer, pancreatic
CFC1 (cardiofaciocutaneous syndrome, type 1 (CFC-1))
CFC2 (cardiofaciocutaneous syndrome, type 2 (CFC-2))
HDGC (cancer, gastric, hereditary diffuse (HDGC))
NS3 (Noonan syndrome, type 3 (NS-3))
OES (Oculoectodermal syndrome, somatic)
SFM (Schimmelpenning-Feuerstein-Mims syndrome, somatic mosaic)
GeneCards KRAS
GeneTests KRAS
Orphanet KRAS

Active transcripts




NCBI ID     

NCBI Protein ID     

00024029 12 transcript variant b NM_004985.3 NP_004976.2 97

Copyright & disclaimer
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