KRAS gene homepage

General information
Gene symbol KRAS
Gene name v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
Chromosome 12
Chromosomal band p12.1
Imprinted Not imprinted
Genomic reference NG_007524.1
Transcript reference NM_004985.3
Exon/intron information NM_004985.3 exon/intron table
Associated with diseases ACLC, AML, cancer, bladder, cancer, pancreatic, CFC-1, CFC-2, HDGC, ID, NS, NS-3, RALD, cancer, breast, familial, Leukemia, acute myelogenous, SFM syndrome, somatic mosaic
Citation reference(s) -
Refseq URL Genomic reference sequence
Curators (1) Etienne Rouleau
Total number of public variants reported 68
Unique public DNA variants reported 51
Individuals with public variants 267
Hidden variants 5
Download all this gene's data Download all data
Notes Establishment of this gene variant database (LSDB) was supported by the European Community's Seventh Framework Programme (FP7/2007-2013) under grant agreement No 200754 - the GEN2PHEN project.
Date created April 29, 2010
Date last updated March 23, 2020
Version KRAS:200323

Graphical displays and utilities
Graphs Graphs displaying summary information of all variants in the database »
Reading frame checker The Reading-frame checker generates a prediction of the effect of whole-exon changes. Active for: NM_004985.3.
UCSC Genome Browser Show variants in the UCSC Genome Browser (full view, compact view)
Ensembl Genome Browser Show variants in the Ensembl Genome Browser (full view, compact view)
NCBI Sequence Viewer Show distribution histogram of variants in the NCBI Sequence Viewer

Links to other resources
Homepage URL
External URL Orphanet
HGNC 6407
Entrez Gene 3845
PubMed articles KRAS
OMIM - Gene 190070
OMIM - Diseases ACLC (cancer, lung (adenocarcinoma))
AML (leukemia, myeloid, acute (AML))
cancer, bladder
cancer, pancreatic
CFC-1 (cardiofaciocutaneous syndrome, type 1 (CFC-1))
CFC-2 (cardiofaciocutaneous syndrome, type 2 (CFC-2))
HDGC (cancer, gastric, hereditary diffuse (HDGC))
NS-3 (Noonan syndrome, type 3 (NS-3))
cancer, breast, familial
SFM syndrome, somatic mosaic
GeneCards KRAS
GeneTests KRAS

Active transcripts




NCBI ID     

NCBI Protein ID     

00024029 12 transcript variant b NM_004985.3 NP_004976.2 68

Copyright & disclaimer
The contents of this LOVD database are the intellectual property of the respective curator(s). Any unauthorised use, copying, storage or distribution of this material without written permission from the curator(s) will lead to copyright infringement with possible ensuing litigation. Copyright © 2010-2020. All Rights Reserved. For further details, refer to Directive 96/9/EC of the European Parliament and the Council of March 11 (1996) on the legal protection of databases.

We have used all reasonable efforts to ensure that the information displayed on these pages and contained in the databases is of high quality. We make no warranty, express or implied, as to its accuracy or that the information is fit for a particular purpose, and will not be held responsible for any consequences arising out of any inaccuracies or omissions. Individuals, organisations and companies which use this database do so on the understanding that no liability whatsoever either direct or indirect shall rest upon the curator(s) or any of their employees or agents for the effects of any product, process or method that may be produced or adopted by any part, notwithstanding that the formulation of such product, process or method may be based upon information here provided.