The APC gene homepage
General information |
Gene symbol |
APC |
Gene name |
adenomatous polyposis coli |
Chromosome |
5 |
Chromosomal band |
q21-q22 |
Imprinted |
Unknown |
Genomic reference |
LRG_130 |
Transcript reference |
NM_000038.5 |
Associated with diseases |
cancer, gastric, cancer, liver, CRC, DESMD, FAP1, polyposis |
Citation reference(s) |
- |
Refseq URL |
Genomic reference sequence |
Curators (3) |
Stefan Aretz, Isabel Spier, and Xiaoyu Sherry Yin |
Total number of public variants reported |
5809 |
Unique public DNA variants reported |
1964 |
Individuals with public variants |
5240 |
Hidden variants |
30 |
Notes |
Aliases for APC: BTPS2, DP2, DP2.5, DP3, GS.
 this is one of the InSiGHT gene variant databases. We gratefully acknowledge the work of Kirsten Wöllner acting as curator (until 2018). |
Date created |
September 09, 2009 |
Date last updated |
November 27, 2023 |
Version |
APC:231127 |
Links to other resources |
Homepage URL |
https://www.LOVD.nl/APC |
External URL |
InSiGHT Institut für Humangenetik, Universität Bonn UMD APC database |
HGNC |
583 |
Entrez Gene |
324 |
PubMed articles |
APC |
OMIM - Gene |
611731 |
OMIM - Diseases |
cancer, gastric (cancer, gastric (Neoplasm of stomach)) cancer, liver (cancer, hepatocellular (HCC)) CRC (cancer, colorectal, susceptibility to (CRC)) DESMD (desmoid disease, hereditary) FAP1 (adenomatous polyposis, familial, type 1 (FAP-1, Gardner syndrome)) |
HGMD |
APC |
GeneCards |
APC |
GeneTests |
APC |
Orphanet |
APC |
Active transcripts
Copyright & disclaimer |
The contents of this LOVD database are the intellectual property of the respective submitter(s) and curator(s) of the individual records. Individual data entries may indicate which data license applies to that specific record. When no license is listed, no permissions are granted. Any unauthorized use, copying, storage, or distribution of this material without written permission from the curator(s) will lead to copyright infringement with possible ensuing litigation. Copyright © 2009-2023. All Rights Reserved. For further details, refer to Directive 96/9/EC of the European Parliament and the Council of March 11 (1996) on the legal protection of databases.
We have used all reasonable efforts to ensure that the information displayed on these pages and contained in the databases is of high quality. We make no warranty, express or implied, as to its accuracy or that the information is fit for a particular purpose, and will not be held responsible for any consequences arising from any inaccuracies or omissions. Individuals, organizations, and companies that use this database do so on the understanding that no liability whatsoever, either direct or indirect, shall rest upon the data submitter(s), curator(s), or any of their employees or agents for the effects of any product, process, or method that may be produced or adopted by any part, notwithstanding that the formulation of such product, process or method may be based upon information here provided. |
|
|