APC gene homepage


General information
Gene symbol APC
Gene name adenomatous polyposis coli
Chromosome 5
Chromosomal band q21-q22
Imprinted Unknown
Genomic reference LRG_130
Transcript reference NM_000038.5
Associated with diseases cancer, gastric, cancer, liver, CRC, FAP-1, HDD, polyposis
Citation reference(s) -
Refseq URL Genomic reference sequence
Curators (3) Stefan Aretz, Kirsten Wöllner and Isabel Spier
Total number of public variants reported 4610
Unique public DNA variants reported 1534
Individuals with public variants 4716
Hidden variants 0
Notes Aliases for APC: BTPS2, DP2, DP2.5, DP3, GS.
this is one of the InSiGHT gene variant databases.
Date created September 09, 2009
Date last updated July 23, 2017
Version APC:170723

Graphical displays and utilities
Graphs Graphs displaying summary information of all variants in the database »
UCSC Genome Browser Show variants in the UCSC Genome Browser (full view, compact view)
Ensembl Genome Browser Show variants in the Ensembl Genome Browser (full view, compact view)
NCBI Sequence Viewer Show distribution histogram of variants in the NCBI Sequence Viewer

Links to other resources
Homepage URL https://www.LOVD.nl/APC
External URL For submissions please use the LOVDv2 databaste
InSiGHT
Institut für Humangenetik, Universität Bonn
Orphanet
UMD APC database
HGNC 583
Entrez Gene 324
PubMed articles APC
OMIM - Gene 611731
OMIM - Diseases cancer, gastric (cancer, gastric (Neoplasm of stomach))
cancer, liver (cancer, hepatocellular)
CRC (cancer, colorectal (CRC))
FAP-1 (adenomatous polyposis, familial, type 1 (FAP-1, Gardner syndrome))
HDD (desmoid disease, hereditary (HDD))
HGMD APC
GeneCards APC
GeneTests APC


Active transcripts


ID     

Chr     

Name     

NCBI ID     

NCBI Protein ID     

DescendingVariants     
00002660 5 transcript variant 3 NM_000038.5 NP_000029.2 4610


Copyright & disclaimer
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